Ivan Gautschi

Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits

Cecilia M. Canessa, Laurent Schild, Gary Buell et al. · Nature · 1994 · 2K citations

Natural Sciences, Biochemistry, Biophysics +13

Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: A quantitative approach

Dmitri Firsov, Laurent Schild, Ivan Gautschi et al. · Proceedings of the National Academy of Sciences · 1996 · 422 citations · Full text

Natural Sciences, Cell Biology, Pharmacology +17

Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome.

Laurent Schild, Yin Lu, Ivan Gautschi et al. · The EMBO Journal · 1996 · 400 citations · Full text

Natural Sciences, Genetics, Molecular Biology +15

A de novo missense mutation of the beta subunit of the epithelial sodium channel causes hypertension and Liddle syndrome, identifying a proline-rich segment critical for regulation of channel activity.

Joni H. Hansson, Laurent Schild, Yin Lu et al. · Proceedings of the National Academy of Sciences · 1995 · 366 citations

Natural Sciences, Genetics, Molecular Genetics +17

A mutation in the epithelial sodium channel causing Liddle disease increases channel activity in the Xenopus laevis oocyte expression system.

Laurent Schild, Cecilia M. Canessa, Richard A. Shimkets et al. · Proceedings of the National Academy of Sciences · 1995 · 312 citations

Life Sciences, Pharmacology, Physiology +17