David B. Simon

Human Hypertension Caused by Mutations in WNK Kinases

Frederick H. Wilson, Sandra Disse-Nicodème, Keith A. Choate et al. · Science · 2001 · 1.5K citations

Life Sciences, Genetics, Molecular Genetics +17

Gitelman's variant of Barter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na–Cl cotransporter

David B. Simon, Carol Nelson‐Williams, Margaret J. Bia et al. · Nature Genetics · 1996 · 1.2K citations

Life Sciences, Genetics, Human Genetics +2

Paracellin-1, a Renal Tight Junction Protein Required for Paracellular Mg ²⁺ Resorption

David B. Simon, Yin Lu, Keith A. Choate et al. · Science · 1999 · 1.1K citations

Life Sciences, Cell Biology, Physiology +17

Bartter's syndrome, hypokalaemic alkalosis with hypercalciuria, is caused by mutations in the Na–K–2CI cotransporter NKCC2

David B. Simon, Fiona E. Karet, Jahed M. Hamdan et al. · Nature Genetics · 1996 · 907 citations

Medicine, Nephrology, Calcium Homeostasis +6

Mutations in the chloride channel gene, CLCNKB, cause Bartter's syndrome type III

David B. Simon, Ranjit S. Bindra, Traci A. Mansfield et al. · Nature Genetics · 1997 · 870 citations

Life Sciences, Genetics, Molecular Genetics +13