Qiuping Ye

Discovery of AMG 232, a Potent, Selective, and Orally Bioavailable MDM2–p53 Inhibitor in Clinical Development

Daqing Sun, Zhihong Li, Yosup Rew et al. · Journal of Medicinal Chemistry · 2014 · 290 citations · Full text

Structure-Based Design of Novel Inhibitors of the MDM2–p53 Interaction

Yosup Rew, Daqing Sun, Felix González-López de Turiso et al. · Journal of Medicinal Chemistry · 2012 · 166 citations · Full text

The MDM2 Inhibitor AMG 232 Demonstrates Robust Antitumor Efficacy and Potentiates the Activity of p53-Inducing Cytotoxic Agents

Jude Canon, Tao Osgood, Steven H. Olson et al. · Molecular Cancer Therapeutics · 2015 · 144 citations

Amg 232, Tumor Biology, P53-inducing Cytotoxic Agents +13

SAR and Mode of Action of Novel Non-Nucleoside Inhibitors of Hepatitis C NS5b RNA Polymerase

Jay P. Powers, Derek E. Piper, Yang Li et al. · Journal of Medicinal Chemistry · 2006 · 125 citations · Full text

Selective and Potent Morpholinone Inhibitors of the MDM2–p53 Protein–Protein Interaction

Ana Z. González, John Eksterowicz, Michael D. Bartberger et al. · Journal of Medicinal Chemistry · 2014 · 83 citations · Full text