Dominik Rüttinger

Targeting Tumor-Associated Macrophages with Anti-CSF-1R Antibody Reveals a Strategy for Cancer Therapy

Carola H. Ries, Michael A. Cannarile, Sabine Hoves et al. · Cancer Cell · 2014 · 1.4K citations

Medicine, Immunology, Oncology +16

CSF1R inhibition with emactuzumab in locally advanced diffuse-type tenosynovial giant cell tumours of the soft tissue: a dose-escalation and dose-expansion phase 1 study

Philippe A. Cassier, Antoîne Italiano, Carlos Gomez-Roca et al. · The Lancet Oncology · 2015 · 363 citations

Medicine, Oncology, Pharmacology +14

Rapid activation of tumor-associated macrophages boosts preexisting tumor immunity

Sabine Hoves, Chia-Huey Ooi, Hadassah Sade et al. · The Journal of Experimental Medicine · 2018 · 215 citations · Full text

Life Sciences, Immunology, Oncology +17

Phase I study of emactuzumab single agent or in combination with paclitaxel in patients with advanced/metastatic solid tumors reveals depletion of immunosuppressive M2-like macrophages

C. Gomez-Roca, Antoîne Italiano, Christophe Le Tourneau et al. · Annals of Oncology · 2019 · 202 citations · Full text

Life Sciences, Immunology, Oncology +16

Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response

Camilla Salvagno, Metamia Ciampricotti, Sander Tuit et al. · Nature Cell Biology · 2019 · 168 citations

Life Sciences, Immunology, Oncology +14