Michael A. Cannarile

Targeting Tumor-Associated Macrophages with Anti-CSF-1R Antibody Reveals a Strategy for Cancer Therapy

Carola H. Ries, Michael A. Cannarile, Sabine Hoves et al. · Cancer Cell · 2014 · 1.3K citations

Cancer Therapy, Tumor Biology, Tumor-associated Macrophages +12

CSF1R inhibition with emactuzumab in locally advanced diffuse-type tenosynovial giant cell tumours of the soft tissue: a dose-escalation and dose-expansion phase 1 study

Philippe A. Cassier, Antoîne Italiano, Carlos Gomez-Roca et al. · The Lancet Oncology · 2015 · 356 citations

Medicine, Immunology, Pathology +9

Transcriptional regulator Id2 mediates CD8+ T cell immunity

Michael A. Cannarile, Nicholas A. Lind, Richard Rivera et al. · Nature Immunology · 2006 · 247 citations

Adaptive Immune System, Immunology, Autoimmunity +5

Rapid activation of tumor-associated macrophages boosts preexisting tumor immunity

Sabine Hoves, Chia-Huey Ooi, Carsten Wolter et al. · The Journal of Experimental Medicine · 2018 · 205 citations · Full text

Rapid Activation, Immune Evasion, Cancer Immunosurveillance +14

Phase I study of emactuzumab single agent or in combination with paclitaxel in patients with advanced/metastatic solid tumors reveals depletion of immunosuppressive M2-like macrophages

C. Gomez-Roca, Antoîne Italiano, Christophe Le Tourneau et al. · Annals of Oncology · 2019 · 189 citations · Full text

Immunosuppressive M2-like Macrophages, Medicine, Metronomic Therapy +6