Concepedia

Author

Julien Lefranc

Bayer (Germany)ORCID

Also Known As

D. Panne, J Lefranc, J. Berge Lefranc, J. Lefranc, Julien Lefranc, Lefranc, J., Lefranc, Julien

58

Publications

1.3K

Citations

14

H-Index

32

Concepts

All Affiliations

Bayer (Germany)Nuvisan (Germany)Shanghai Institute of Organic ChemistryUniversity of Chinese Academy of SciencesBayer (United States)
JL

About

Julien Lefranc is an author at Bayer (Germany) specializing in medicine, tumor biology, and cancer research.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

4

4

108

2

Engineering

2

2

70

3

Natural Sciences

1

1

12

4

Biochemistry

1

1

51

5

Biomolecular Engineering

1

1

51

Julien Lefranc

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13

Publications

825

Citations

12

H-Index

YearCitations

The Novel ATR Inhibitor BAY 1895344 Is Efficacious as Monotherapy and Combined with DNA Damage–Inducing or Repair–Compromising Therapies in Preclinical Cancer Models

Antje M. Wengner, Gerhard Siemeister, Ulrich Lücking,

Molecular Cancer Therapeutics

2019

200

Discovery and SAR of Novel 2,3‐Dihydroimidazo[1,2‐<i>c</i>]quinazoline PI3K Inhibitors: Identification of Copanlisib (BAY 80‐6946)

William J. Scott, Martin Hentemann, R. Rowley,

ChemMedChem

2016

111

Nickel‐Catalyzed <i>N</i>‐Arylation of <i>NH</i>‐Sulfoximines with Aryl Halides via Paired Electrolysis

Dong Liu, Zhao‐Ran Liu, Cong Ma,

Angewandte Chemie International Edition

2021

96

Damage Incorporated: Discovery of the Potent, Highly Selective, Orally Available ATR Inhibitor BAY 1895344 with Favorable Pharmacokinetic Properties and Promising Efficacy in Monotherapy and in Combination Treatments in Preclinical Tumor Models

Ulrich Lücking, Lars Wortmann, Antje M. Wengner,

Journal of Medicinal Chemistry

2020

68

Tandem β-Alkylation−α-Arylation of Amines by Carbolithiation and Rearrangement of <i>N</i>-Carbamoyl Enamines (Vinyl Ureas)

Jonathan Clayden, Morgan Donnard, Julien Lefranc,

Journal of the American Chemical Society

2010

66

Targeting the aryl hydrocarbon receptor (AhR) with BAY 2416964: a selective small molecule inhibitor for cancer immunotherapy

Christina Kober, Julian Roewe, Norbert Schmees,

Journal for ImmunoTherapy of Cancer

2023

64

Intramolecular Vinylation of Secondary and Tertiary Organolithiums

Julien Lefranc, Anne M. Fournier, Gaëlle Mingat,

Journal of the American Chemical Society

2012

51

Discovery of BAY-985, a Highly Selective TBK1/IKKε Inhibitor

Julien Lefranc, Volker Schulze, R.C. Hillig,

Journal of Medicinal Chemistry

2019

46

Amines Bearing Tertiary Substituents by Tandem Enantioselective Carbolithiation–Rearrangement of Vinylureas

Michael Tait, Morgan Donnard, Alberto Minassi,

Organic Letters

2012

42

The potent AMPK inhibitor BAY-3827 shows strong efficacy in androgen-dependent prostate cancer models

Clara Lemos, Volker Schulze, Simon J. Baumgart,

Cellular Oncology

2021

40

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