Nickel‐Catalyzed <i>N</i>‐Arylation of <i>NH</i>‐Sulfoximines with Aryl Halides via Paired Electrolysis

Abstract

A novel strategy for the N-arylation of NH-sulfoximines has been developed by merging nickel catalysis and electrochemistry (in an undivided cell), thereby providing a practical method for the construction of sulfoximine derivatives. Paired electrolysis is employed in this protocol, so a sacrificial anode is not required. Owing to the mild reaction conditions, excellent functional group tolerance and yield are achieved. A preliminary mechanistic study indicates that the anodic oxidation of a Ni^II species is crucial to promote the reductive elimination of a C-N bond from the resulting Ni^III species at room temperature.