Linus Hyun

Engineered antibody Fc variants with enhanced effector function

Greg A. Lazar, Wei Dang, Sher Karki et al. · Proceedings of the National Academy of Sciences · 2006 · 783 citations · Full text

Engineered Fc Regions, Novel Therapy, Antibody Fc Variants +13

Inactivation of TNF Signaling by Rationally Designed Dominant-Negative TNF Variants

Paul M. Steed, Malú G. Tansey, Jonathan Zalevsky et al. · Science · 2003 · 257 citations

Immunology, Cell Death, Pathology +18

Mechanisms of self-association of a human monoclonal antibody CNTO607

Deidra Bethea, Sheng‐Jiun Wu, Jinquan Luo et al. · Protein Engineering Design and Selection · 2012 · 77 citations · Full text

Protein Assembly, Immunology, Molecular Biology +17

Selection of high-affinity Centyrin FN3 domains from a simple library diversified at a combination of strand and loop positions

Michael Diem, Linus Hyun, Yi Fang et al. · Protein Engineering Design and Selection · 2014 · 61 citations

Protein Assembly, Molecular Biology, Alternative Scaffold Molecules +21