Carla A. Donatelli

Discovery of GSK2126458, a Highly Potent Inhibitor of PI3K and the Mammalian Target of Rapamycin

Steven D. Knight, Nicholas D. Adams, Joelle L. Burgess et al. · ACS Medicinal Chemistry Letters · 2010 · 372 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Discovery of GSK1070916, a Potent and Selective Inhibitor of Aurora B/C Kinase

Nicholas D. Adams, Jerry L. Adams, Joelle L. Burgess et al. · Journal of Medicinal Chemistry · 2010 · 111 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Novel ATP-Competitive Kinesin Spindle Protein Inhibitors

Cynthia A. Parrish, Nicholas D. Adams, Kurt R. Auger et al. · Journal of Medicinal Chemistry · 2007 · 74 citations · Full text

Medicine, Medicinal Chemistry, Oncology +15

Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295

Xiangping Qian, Andrew McDonald, Han-Jie Zhou et al. · ACS Medicinal Chemistry Letters · 2010 · 64 citations

Pharmacy, Medicinal Chemistry, Pharmacology +7

Design and Optimization of Sulfone Pyrrolidine Sulfonamide Antagonists of Transient Receptor Potential Vanilloid-4 with in Vivo Activity in a Pulmonary Edema Model

Joseph E. Pero, Jay M. Matthews, David J. Behm et al. · Journal of Medicinal Chemistry · 2018 · 34 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17