Jennifer Berbaum

JD-5006 and JD-5037: Peripherally restricted (PR) cannabinoid-1 receptor blockers related to SLV-319 (Ibipinabant) as metabolic disorder therapeutics devoid of CNS liabilities

Robert J. Chorvat, Jennifer Berbaum, Kristine Seriacki et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 88 citations · Full text

Cns Liabilities, Cannabis Use, Functional Selectivity +8

GENERATION AND VALIDATION OF RAPID COMPUTATIONAL FILTERS FOR CYP2D6 AND CYP3A4

Sean Ekins, Jennifer Berbaum, Richard K. Harrison · Drug Metabolism and Disposition · 2003 · 77 citations

Structure-Based Design and Synthesis of 1,3-Oxazinan-2-one Inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1

Zhenrong Xu, Colin M. Tice, Wei Zhao et al. · Journal of Medicinal Chemistry · 2011 · 40 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Cellular Potency +14

Spirocyclic ureas: Orally bioavailable 11β-HSD1 inhibitors identified by computer-aided drug design

Colin M. Tice, Wei Zhao, Zhenrong Xu et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 25 citations · Full text

Medicinal Chemistry, Urology, Bioavailable 11β-Hsd1 Inhibitors +11

Optimization of orally bioavailable alkyl amine renin inhibitors

Zhenrong Xu, Salvacion Cacatian, Jing Yuan et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 18 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Medicine +6