Salvacion Cacatian

Structure-Based Design and Synthesis of 1,3-Oxazinan-2-one Inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1

Zhenrong Xu, Colin M. Tice, Wei Zhao et al. · Journal of Medicinal Chemistry · 2011 · 40 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Cellular Potency +14

Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility

Lanqi Jia, R. David Simpson, Jing Yuan et al. · ACS Medicinal Chemistry Letters · 2011 · 38 citations · Full text

Methyl Group, Hypertension, Medicinal Chemistry +14

Spirocyclic ureas: Orally bioavailable 11β-HSD1 inhibitors identified by computer-aided drug design

Colin M. Tice, Wei Zhao, Zhenrong Xu et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 25 citations · Full text

Medicinal Chemistry, Urology, Bioavailable 11β-Hsd1 Inhibitors +11

Synthesis of allyl phosphine oxides/boranes via Horner reaction of bis(diphenylphosphine)ethane monoxide reagent with an aldehyde

Salvacion Cacatian, P. L. Fuchs · Tetrahedron · 2003 · 24 citations

Ethane Monoxide Reagent, Chemical Engineering, Engineering +9

Optimization of orally bioavailable alkyl amine renin inhibitors

Zhenrong Xu, Salvacion Cacatian, Jing Yuan et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 18 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Medicine +6