Yasin Pourfarjam

Pan-KRAS inhibitor disables oncogenic signalling and tumour growth

Dong-Sung Kim, Lorenz Herdeis, Dorothea Rudolph et al. · Nature · 2023 · 497 citations · Full text

Medicine, Oncology, Pharmacology +17

Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS

Christopher J. Schulze, Kyle J. Seamon, Yulei Zhao et al. · Science · 2023 · 232 citations · Full text

Medicine, Medicinal Chemistry, Oncology +17

Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death

Jerry H. Houl, Zu Ye, Chris A. Brosey et al. · Nature Communications · 2019 · 132 citations · Full text

Medicine, Cancer Biology, Oncology +16

Androgen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly

Chunsong Yang, Kasey Jividen, Teddy Kamata et al. · Nature Communications · 2021 · 44 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Effect of Cichorium intybus L. on the expression of hepatic NF-κB and IKKβ and serum TNF-α in STZ− and STZ+ niacinamide-induced diabetes in rats

Lotfollah Rezagholizadeh, Yasin Pourfarjam, Azin Nowrouzi et al. · Diabetology & Metabolic Syndrome · 2016 · 35 citations · Full text

Medicine, Immunology, Pharmacology +15