Kathryn Loving

Applying Physics-Based Scoring to Calculate Free Energies of Binding for Single Amino Acid Mutations in Protein-Protein Complexes

Hege S. Beard, Anuradha Cholleti, David A. Pearlman et al. · PLoS ONE · 2013 · 282 citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17

Energetic analysis of fragment docking and application to structure-based pharmacophore hypothesis generation

Kathryn Loving, Noeris K. Salam, Woody Sherman · Journal of Computer-Aided Molecular Design · 2009 · 167 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Anti-EFNA4 Calicheamicin Conjugates Effectively Target Triple-Negative Breast and Ovarian Tumor-Initiating Cells to Result in Sustained Tumor Regressions

Marc Damelin, Alexander J. Bankovich, Albert Park et al. · Clinical Cancer Research · 2015 · 87 citations · Full text

Medicine, Oncology, Pharmacology +17

Structure-Based Druggability Assessment of the Mammalian Structural Proteome with Inclusion of Light Protein Flexibility

Kathryn Loving, Andy Lin, Alan C. Cheng · PLoS Computational Biology · 2014 · 36 citations · Full text

Life Sciences, Biochemistry, Drug Discovery +13

FLT3 OR CD33 NOT EMCN Logic Gated CAR-NK Cell Therapy (SENTI-202) for Precise Targeting of AML

Brian S. Garrison, Han‐Xiang Deng, Gözde Yücel et al. · Blood · 2021 · 17 citations

Medicine, Cancer Biology, Oncology +14