Han‐Xiang Deng

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

D.R. Rosen, Teepu Siddique, David T. Patterson et al. · Nature · 1993 · 7K citations

Life Sciences, Genetics, Neuroscience +14

Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase Mutation

Mark E. Gurney, Haifeng Pu, Arlene Y. Chiu et al. · Science · 1994 · 4.1K citations

Life Sciences, Genetics, Neuroscience +17

The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis

Yi Yang, Afif Hentati, Han‐Xiang Deng et al. · Nature Genetics · 2001 · 732 citations

Life Sciences, Genetics, Molecular Genetics +12

Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria

Han‐Xiang Deng, Yong Shi, Yoshiaki Furukawa et al. · Proceedings of the National Academy of Sciences · 2006 · 419 citations · Full text

Life Sciences, Neurology, Neuroscience +17

FUS‐immunoreactive inclusions are a common feature in sporadic and non‐SOD1 familial amyotrophic lateral sclerosis

Han‐Xiang Deng, Hong Zhai, Eileen H. Bigio et al. · Annals of Neurology · 2010 · 352 citations · Full text

Medicine, Neurology, Neuroscience +15