Alan Kennedy

Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations

Desirée Schubert, Claudia Bode, Rupert Kenefeck et al. · Nature Medicine · 2014 · 805 citations · Full text

Immunogenetics, Autoimmune Disease, Immunodeficiencies +12

Monogenic causes of chronic kidney disease in adults

Dervla M. Connaughton, Claire Kennedy, Shirlee Shril et al. · Kidney International · 2019 · 262 citations

Glomerular Disease, Glomerulonephritis, Renal Disease +7

Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation

Alan Kennedy, Erin Waters, Behzad Rowshanravan et al. · Nature Immunology · 2022 · 193 citations · Full text

Ctla-4 Recycling, Lymphocyte Development, T-regulatory Cell +17

Treg Cell Function in Rheumatoid Arthritis Is Compromised by CTLA‐4 Promoter Methylation Resulting in a Failure to Activate the Indoleamine 2,3‐Dioxygenase Pathway

Adam P. Cribbs, Alan Kennedy, Henry Penn et al. · Arthritis & Rheumatology · 2014 · 156 citations

Methotrexate Restores Regulatory T Cell Function Through Demethylation of the FoxP3 Upstream Enhancer in Patients With Rheumatoid Arthritis

Adam P. Cribbs, Alan Kennedy, Henry Penn et al. · Arthritis & Rheumatology · 2015 · 154 citations