Alessandro T. Caputo

Author

University of Oxford ORCID

Also Known As

A Caputo, A.T. Caputo, Alessandro T. Caputo, Alessandro Caputo, Alessandro T. Caputo, Alessandro Thanasis Caputo

Publications

933

Citations

H-Index

Concepts

All Affiliations

University of Oxford Toyama University Hospital University of Toyama CSIRO Manufacturing La Jolla Institute for Immunology

About

Alessandro T. Caputo is an author at University of Oxford specializing in medicine, biochemistry, and molecular biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	6	6	540
2	Biochemistry	5	5	389
3	Natural Sciences	3	3	263
4	Engineering	1	1	84
5	Biology	1	1	60

Alessandro T. Caputo

Publications

889

Citations

H-Index

Page 1

	Year	Citations
Design and Synthesis of Novel Lactate Dehydrogenase A Inhibitors by Fragment-Based Lead Generation Richard A. Ward, C. Brassington, Alexander L. Breeze, Journal of Medicinal Chemistry Aldo-keto ReductaseMolecular BiologyLead IdentificationChemical BiologyMedicinal Chemistry	2012	169
Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels Oliver B. Clarke, Alessandro T. Caputo, Adam P. Hill, Cell Biophysical ModelingSignal TransductionMolecular PhysiologyDomain ReorientationHyperpolarization (Biology)	2010	151
Structures of mammalian ER α-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals Alessandro T. Caputo, Dominic S. Alonzi, Lucia Marti, Proceedings of the National Academy of Sciences	2016	91
Iminosugars Inhibit Dengue Virus Production via Inhibition of ER Alpha-Glucosidases—Not Glycolipid Processing Enzymes Andrew C. Sayce, Dominic S. Alonzi, Sarah S. Killingbeck, PLoS neglected tropical diseases EngineeringMany IminosugarsGlycobiologyImmunologyImmunotherapeutics	2016	84
Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4 Kelly L. Warfield, Emily M. Plummer, Andrew C. Sayce, Antiviral Research	2016	67
Interdomain conformational flexibility underpins the activity of UGGT, the eukaryotic glycoprotein secretion checkpoint Pietro Roversi, Lucia Marti, Alessandro T. Caputo, Proceedings of the National Academy of Sciences	2017	64
Targeting Endoplasmic Reticulum α-Glucosidase I with a Single-Dose Iminosugar Treatment Protects against Lethal Influenza and Dengue Virus Infections Kelly L. Warfield, Dominic S. Alonzi, Johan C. Hill, Journal of Medicinal Chemistry	2020	63
Ancestral Sequence Reconstruction Identifies Structural Changes Underlying the Evolution of <i>Ideonella sakaiensis</i> PETase and Variants with Improved Stability and Activity Yvonne Joho, Vanessa Vongsouthi, Matthew A. Spence, Biochemistry Ancestral Protein ReconstructionImproved StabilityGeneticsMolecular BiologyGenomics	2022	60
Low pH and Anionic Lipid-dependent Fusion of Uukuniemi Phlebovirus to Liposomes David Bitto, Steinar Halldórsson, Alessandro T. Caputo, Journal of Biological Chemistry Membrane FusionVirus StructureViral ReplicationUukuniemi PhlebovirusMolecular Virology	2016	42
ToP-DNJ, a Selective Inhibitor of Endoplasmic Reticulum α-Glucosidase II Exhibiting Antiflaviviral Activity J. L. Kiappes, Michelle L. Hill, Dominic S. Alonzi, ACS Chemical Biology Viral ImmunityImmunologyBiological TherapyImmunotherapeuticsInnate Immunity	2017	34

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