Donald J. Foster

Advanced siRNA Designs Further Improve In Vivo Performance of GalNAc-siRNA Conjugates

Donald J. Foster, Christopher R. Brown, Sarfraz Shaikh et al. · Molecular Therapy · 2018 · 294 citations · Full text

Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates

Kirk Brown, Jayaprakash K. Nair, Maja M. Janas et al. · Nature Biotechnology · 2022 · 225 citations · Full text

Rnai Therapeutics, Liver Physiology, Gene Delivery +5

5′‐(<i>E</i>)‐Vinylphosphonate: A Stable Phosphate Mimic Can Improve the RNAi Activity of siRNA–GalNAc Conjugates

Rubina Parmar, Jennifer L. S. Willoughby, Jingxuan Liu et al. · ChemBioChem · 2016 · 132 citations

Preclinical evaluation of RNAi as a treatment for transthyretin-mediated amyloidosis

James S. Butler, Amy Chan, Susete Costelha et al. · Amyloid · 2016 · 114 citations · Full text

Translational Medicine, Attr Amyloidosis, Ttr Amyloid +13

Activation of LDL Receptor Expression by Small RNAs Complementary to a Noncoding Transcript that Overlaps the LDLR Promoter

Masayuki Matsui, Fuminori Sakurai, Sayda M. Elbashir et al. · Chemistry & Biology · 2010 · 102 citations

Functional Genomics, Signal Transduction, Natural Sciences +9