Alexander R. Guimarães

Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

Haoqiang Ying, Alec C. Kimmelman, Costas A. Lyssiotis et al. · Cell · 2012 · 2K citations · Full text

Pancreatic Cancer, Oncogenic Agent, Medicine +7

Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers

Jeffrey A. Engelman, Liang Chen, Xiaohong Tan et al. · Nature Medicine · 2008 · 1.3K citations · Full text

Effective Use, Mek Inhibitors, Oncology +9

The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α

Lei Zhong, Agustina D’Urso, Debra Toiber et al. · Cell · 2010 · 980 citations · Full text

Histone Modifications, Chromatin, Transcriptional Regulation +10

The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism

Carlos Sebastián, Bernadette Zwaans, Dafne M. Silberman et al. · Cell · 2012 · 651 citations · Full text

Histone Modifications, Epigenetic Change, Histone Deacetylase Sirt6 +16

Metrology Standards for Quantitative Imaging Biomarkers

Daniel C. Sullivan, Nancy A. Obuchowski, Larry G. Kessler et al. · Radiology · 2015 · 404 citations · Full text

Engineering, Advanced Imaging, Diagnosis +21