Lawrence L. Hirschberger

Discovery and Characterization of a Second Mammalian Thiol Dioxygenase, Cysteamine Dioxygenase

John E. Dominy, C.R. Simmons, Lawrence L. Hirschberger et al. · Journal of Biological Chemistry · 2007 · 186 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Synthesis of Amino Acid Cofactor in Cysteine Dioxygenase Is Regulated by Substrate and Represents a Novel Post-translational Regulation of Activity

John E. Dominy, Jesse Hwang, S. Guo et al. · Journal of Biological Chemistry · 2008 · 124 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Knockout of the murine cysteine dioxygenase gene results in severe impairment in ability to synthesize taurine and an increased catabolism of cysteine to hydrogen sulfide

Iori Ueki, Heather B. Roman, Alessandro Valli et al. · American Journal of Physiology-Endocrinology and Metabolism · 2011 · 123 citations · Full text

Life Sciences, Biochemistry, Physiology +13

HepG2/C3A cells respond to cysteine deprivation by induction of the amino acid deprivation/integrated stress response pathway

Jeong-In Lee, John E. Dominy, Angelos K. Sikalidis et al. · Physiological Genomics · 2008 · 101 citations

Life Sciences, Biochemistry, Molecular Biology +17

Regulation of cysteine dioxygenase degradation is mediated by intracellular cysteine levels and the ubiquitin–26 S proteasome system in the living rat

John E. Dominy, Lawrence L. Hirschberger, Relicardo M. Coloso et al. · Biochemical Journal · 2006 · 97 citations · Full text

Life Sciences, Biochemistry, Nutritional Sciences +16