Heather B. Roman

Knockout of the murine cysteine dioxygenase gene results in severe impairment in ability to synthesize taurine and an increased catabolism of cysteine to hydrogen sulfide

Iori Ueki, Heather B. Roman, Alessandro Valli et al. · American Journal of Physiology-Endocrinology and Metabolism · 2011 · 121 citations · Full text

Cysteine Homeostasis, Lipid Peroxidation, Redox Biology +16

The Cysteine Dioxgenase Knockout Mouse: Altered Cysteine Metabolism in Nonhepatic Tissues Leads to Excess H ₂ S/HS ⁻ Production and Evidence of Pancreatic and Lung Toxicity

Heather B. Roman, Lawrence L. Hirschberger, Jakub Krijt et al. · Antioxidants and Redox Signaling · 2013 · 68 citations · Full text

Extrahepatic tissues compensate for loss of hepatic taurine synthesis in mice with liver-specific knockout of cysteine dioxygenase

Iori Ueki, Heather B. Roman, Lawrence L. Hirschberger et al. · American Journal of Physiology-Endocrinology and Metabolism · 2012 · 51 citations · Full text

Plasma Cysteine Levels, Lipid Peroxidation, Extrahepatic Tissues +20

Upregulation of capacity for glutathione synthesis in response to amino acid deprivation: regulation of glutamate–cysteine ligase subunits

Angelos K. Sikalidis, Kevin M. Mazor, Jeong-In Lee et al. · Amino Acids · 2014 · 39 citations · Full text

Acid Deprivation, Biochemistry, Physiology +7

Primary hepatocytes from mice lacking cysteine dioxygenase show increased cysteine concentrations and higher rates of metabolism of cysteine to hydrogen sulfide and thiosulfate

Halina Jurkowska, Heather B. Roman, Lawrence L. Hirschberger et al. · Amino Acids · 2014 · 38 citations · Full text

Lipid Peroxidation, Redox Biology, Carbonyl Metabolism +16