Nicholas T. Hertz

Drugging MYCN through an Allosteric Transition in Aurora Kinase A

W. Clay Gustafson, Justin Meyerowitz, Erin A. Nekritz et al. · Cancer Cell · 2014 · 273 citations · Full text

Signal Transduction, Molecular Regulation, Natural Sciences +11

A Neo-Substrate that Amplifies Catalytic Activity of Parkinson’s-Disease-Related Kinase PINK1

Nicholas T. Hertz, Amandine Berthet, Martin L. Sos et al. · Cell · 2013 · 267 citations · Full text

Neurodegenerative Diseases, Signal Transduction, Molecular Neuroscience +10

A Raf-induced allosteric transition of KSR stimulates phosphorylation of MEK

Damian F. Brennan, Arvin C. Dar, Nicholas T. Hertz et al. · Nature · 2011 · 253 citations

Signal Transduction, Cell Regulation, Signaling Pathway +11

CRISPR–Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity

Nicholas J. Kramer, Michael S. Haney, David W. Morgens et al. · Nature Genetics · 2018 · 235 citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Synaptic Signaling +12

Identification of AMPK Phosphorylation Sites Reveals a Network of Proteins Involved in Cell Invasion and Facilitates Large-Scale Substrate Prediction

Bethany E. Schaffer, Rebecca S. Levin, Nicholas T. Hertz et al. · Cell Metabolism · 2015 · 181 citations · Full text

Signal Transduction, Ampk Phosphorylation Sites, Signaling Pathway +14