Concepedia

Arvin C. Dar

AC

25

Publications

2.8K

Citations

21

H-Index

2002

Active since

Affiliations

Icahn School of Medicine at Mount Sinai(Current)

University of California, San Francisco

University of Toronto

Mount Sinai Hospital

Lunenfeld-Tanenbaum Research Institute

Arvin C. Dar is an author at Icahn School of Medicine at Mount Sinai specializing in medicine, molecular biology, and natural sciences.

Top concepts

MedicineMolecular BiologyCell BiologyNatural SciencesCell SignalingSignal TransductionPharmacologyDrug DiscoverySystems BiologyRadiation Oncology

Publications per year

2002–2024

25

Publications

25

Higher-Order Substrate Recognition of eIF2α by the RNA-Dependent Protein Kinase PKR

Arvin C. Dar, Thomas Dever, Frank Sicheri · Cell · 2005 · 385 citations · Full text

Molecular Physiology, Signal Transduction, Signaling Pathway +11

Mechanistic Link between PKR Dimerization, Autophosphorylation, and eIF2α Substrate Recognition

Madhusudan Dey, Chune Cao, Arvin C. Dar et al. · Cell · 2005 · 362 citations · Full text

Signal Transduction, Signaling Pathway, Biochemistry +8

Chemical genetic discovery of targets and anti-targets for cancer polypharmacology

Arvin C. Dar, Tirtha K. Das, Kevan M. Shokat et al. · Nature · 2012 · 344 citations

Chemical Genetic Discovery, Drug Target, Medicine +8

Formin Leaky Cap Allows Elongation in the Presence of Tight Capping Proteins

Sally H. Zigmond, Marie Evangelista, Charles Boone et al. · Current Biology · 2003 · 262 citations · Full text

Protein Secretion, Protein Function, Protein Folding +10

A Raf-induced allosteric transition of KSR stimulates phosphorylation of MEK

Damian F. Brennan, Arvin C. Dar, Nicholas T. Hertz et al. · Nature · 2011 · 253 citations

Signal Transduction, Cell Regulation, Signaling Pathway +11

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