Systematic Genetic Analysis with Ordered Arrays of Yeast Deletion Mutants

Amy H.Y. Tong, Marie Evangelista, Ainslie B. Parsons, +10

Science

Role of Formins in Actin Assembly: Nucleation and Barbed-End Association

David Pruyne, Marie Evangelista, Changsong Yang, +4

Science

Protein FunctionProtein AssemblyProtein FoldingFormin HomologyMedicine +13

A Combined Experimental and Computational Strategy to Define Protein Interaction Networks for Peptide Recognition Modules

Amy H.Y. Tong, Becky Drees, Giuliano Nardelli, +13

Science

Molecular BiologyComputational StrategyProtein FoldingBiological NetworkProteomics +19

Bni1p, a Yeast Formin Linking Cdc42p and the Actin Cytoskeleton During Polarized Morphogenesis

Marie Evangelista, Kelly Blundell, Mark S. Longtine, +5

Science

Molecular BiologyCell PolarizationCytoskeletonMolecular GeneticsPolarized Morphogenesis +16

Formins direct Arp2/3-independent actin filament assembly to polarize cell growth in yeast

Marie Evangelista, David Pruyne, David C. Amberg, +2

Nature Cell Biology

MedicineNatural SciencesMolecular BiologyYeastCell Motility +7

A Specificity Map for the PDZ Domain Family

Raffi Tonikian, Yingnan Zhang, Stephen L. Sazinsky, +15

PLoS Biology

Specificity ProfilingMolecular BiologyTopological PropertySpecificity MapBinding Site +15

Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors

Anneleen Daemen, David Peterson, Nisebita Sahu, +19

Proceedings of the National Academy of Sciences

Metabolomic ProfilingPathologyMetabolic RemodelingPdac Clinical SamplesTumor Biology +22

The Cancer Stem Cell Marker Aldehyde Dehydrogenase Is Required to Maintain a Drug-Tolerant Tumor Cell Subpopulation

Debasish Raha, Timothy R. Wilson, Jing Peng, +6

Cancer Research

Formin Leaky Cap Allows Elongation in the Presence of Tight Capping Proteins

Sally H. Zigmond, Marie Evangelista, Charles Boone, +5

Current Biology

Protein SecretionProtein FunctionProtein FoldingCell AdhesionNatural Sciences +8

Kinetics of Hedgehog-Dependent Full-Length Gli3 Accumulation in Primary Cilia and Subsequent Degradation

Xiaohui Wen, Cary Lai, Marie Evangelista, +3

Molecular and Cellular Biology

Environmental SignalingIntraflagellar TransportSynaptic SignalingCellular PhysiologySignaling Pathway +15