Hachiro Sugimoto

Synthesis and Structure-Activity Relationships of Acetylcholinesterase Inhibitors: 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine Hydrochloride and Related Compounds

Hachiro Sugimoto, Youichi Iimura, Yoshiharu Yamanishi et al. · Journal of Medicinal Chemistry · 1995 · 337 citations · Full text

Microglia‐derived interleukin‐6 and leukaemia inhibitory factor promote astrocytic differentiation of neural stem/progenitor cells

Masaya Nakanishi, Tetsuhiro Niidome, Satoru Matsuda et al. · European Journal of Neuroscience · 2007 · 321 citations

Flavonols and flavones as BACE-1 inhibitors: Structure–activity relationship in cell-free, cell-based and in silico studies reveal novel pharmacophore features

Yoshiari Shimmyo, Takeshi Kihara, Akinori Akaike et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 2008 · 232 citations

Structure–activity Relationship, Molecular Pharmacology, Medicinal Chemistry +11

Nicotinic Acetylcholine Receptor-Mediated Neuroprotection by Donepezil Against Glutamate Neurotoxicity in Rat Cortical Neurons

Yuki Takada, Atsushi Yonezawa, Toshiaki Kume et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 206 citations

Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase cascade

Yuki Takada‐Takatori, Toshiaki Kume, Mitsuhiro Sugimoto et al. · Neuropharmacology · 2006 · 184 citations

Alzheimer's Disease, Phosphatidylinositol 3-Kinase Cascade, Dementia +14