Yoshiari Shimmyo

Flavonols and flavones as BACE-1 inhibitors: Structure–activity relationship in cell-free, cell-based and in silico studies reveal novel pharmacophore features

Yoshiari Shimmyo, Takeshi Kihara, Akinori Akaike et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 2008 · 232 citations

Structure–activity Relationship, Molecular Pharmacology, Medicinal Chemistry +11

Multifunction of myricetin on Aβ: Neuroprotection via a conformational change of Aβ and reduction of Aβ via the interference of secretases

Yoshiari Shimmyo, Takeshi Kihara, Akinori Akaike et al. · Journal of Neuroscience Research · 2007 · 124 citations

Epigallocatechin-3-gallate and curcumin suppress amyloid beta-induced beta-site APP cleaving enzyme-1 upregulation

Yoshiari Shimmyo, Takeshi Kihara, Akinori Akaike et al. · Neuroreport · 2008 · 114 citations

Three distinct neuroprotective functions of myricetin against glutamate‐induced neuronal cell death: Involvement of direct inhibition of caspase‐3

Yoshiari Shimmyo, Takeshi Kihara, Akinori Akaike et al. · Journal of Neuroscience Research · 2008 · 85 citations · Full text

Neuronal Cell Death, Cell Death, Direct Inhibition +18

Distinct mechanisms underlie distinct polyphenol‐induced neuroprotection

Keiko Yazawa, Takeshi Kihara, Huilian Shen et al. · FEBS Letters · 2006 · 70 citations

Distinct Mechanisms, Glutamate Excitotoxicity, Social Sciences +18