Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase cascade

Alzheimer's Disease and Senile Dementia: Loss of Neurons in the Basal Forebrain

PJ Whitehouse, DL Price, R. G. Struble et al. · Science · 1982 · 3.6K citations

Life Sciences, Neurobiology, Neuroscience +17

Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt

Luis del Peso, Maribel González-Garcı́a, Carmen Page et al. · Science · 1997 · 2.2K citations

Life Sciences, Cell Biology, Immunology +17

Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures.

Emanuela Bonfoco, Dimitri Krainc, Maria Ankarcrona et al. · Proceedings of the National Academy of Sciences · 1995 · 2K citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis

A H Wyllie, R. G. Morris, Alex Smith et al. · The Journal of Pathology · 1984 · 1.6K citations

Life Sciences, Cell Biology, Molecular Biology +16

Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease.

R.C.A. Pearson, Margaret M. Esiri, R. W. Hiorns et al. · Proceedings of the National Academy of Sciences · 1985 · 1K citations · Full text

Medicine, Neurology, Neuroscience +16