Yoshiharu Yamanishi

Synthesis and Structure-Activity Relationships of Acetylcholinesterase Inhibitors: 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine Hydrochloride and Related Compounds

Hachiro Sugimoto, Youichi Iimura, Yoshiharu Yamanishi et al. · Journal of Medicinal Chemistry · 1995 · 339 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Effect of donepezil hydrochloride (E2020) on basal concentration of extracellular acetylcholine in the hippocampus of rats

Takashi Kosasa, Yuka Kuriya, Kenji Matsui et al. · European Journal of Pharmacology · 1999 · 92 citations

Life Sciences, Neuroscience, Pharmacology +13

Inhibitory effects of donepezil hydrochloride (E2020) on cholinesterase activity in brain and peripheral tissues of young and aged rats

Takashi Kosasa, Yuka Kuriya, Kenji Matsui et al. · European Journal of Pharmacology · 1999 · 69 citations

Medicine, Neuroscience, Pharmacology +11

Synthesis and anti-acetylcholinesterase activity of 1-benzyl-4-[(5,6-dimethoxy-1-indanon-2-yl)methyl]piperidine hydrochloride (E2020) and related compounds

Hachiro Sugimoto, Youichi Iimura, Yoshiharu Yamanishi et al. · Bioorganic & Medicinal Chemistry Letters · 1992 · 67 citations

Life Sciences, Chemistry, Pharmacology +14

Conformational analyses and molecular-shape comparisons of a series of indanone-benzylpiperidine inhibitors of acetylcholinesterase

Mario Cardozo, Takatoshi Kawai, Youichi Iimura et al. · Journal of Medicinal Chemistry · 1992 · 65 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17