Valeria Rachela Villella

Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition

Alessandro Luciani, Valeria Rachela Villella, Speranza Esposito et al. · Nature Cell Biology · 2010 · 452 citations

Inflammation, Cell Autophagy, Mitophagy +11

Targeting the Intracellular Environment in Cystic Fibrosis: Restoring Autophagy as a Novel Strategy to Circumvent the CFTR Defect

Valeria Rachela Villella, Speranza Esposito, Emanuela M. Bruscia et al. · Frontiers in Pharmacology · 2013 · 388 citations · Full text

Cell Autophagy, Mitophagy, Fibrosis +15

Lysosomal accumulation of gliadin p31–43 peptide induces oxidative stress and tissue transglutaminase-mediated PPARγ downregulation in intestinal epithelial cells and coeliac mucosa

Alessandro Luciani, Valeria Rachela Villella, Angela Vasaturo et al. · Gut · 2009 · 144 citations

Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation

Daniela De Stefano, Valeria Rachela Villella, Speranza Esposito et al. · Autophagy · 2014 · 142 citations · Full text

Human Cystic Fibrosis, Inflammatory Lung Disease, Lung Inflammation +16

Tissue Transglutaminase Activation Modulates Inflammation in Cystic Fibrosis via PPARγ Down-Regulation

Luigi Maiuri, Alessandro Luciani, Ida Giardino et al. · The Journal of Immunology · 2008 · 117 citations