Alan Collis

The discovery of RPR 200765A, a p38 MAP kinase inhibitor displaying a good oral anti-arthritic efficacy

Iain M. McLay, Frank Halley, John E. Souness et al. · Bioorganic & Medicinal Chemistry · 2001 · 78 citations

Rheumatoid Disorder, Rheumatology, Anti-inflammatory +8

An Algorithm-Directed Two-Component Library Synthesized Via Solid-Phase Methodology Yielding Potent and Orally Bioavailable p38 MAP Kinase Inhibitors

Jeffrey M. McKenna, Frank Halley, John E. Souness et al. · Journal of Medicinal Chemistry · 2002 · 73 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Drug Target +13

Discovery of novel N-hydroxy-2-arylisoindoline-4-carboxamides as potent and selective inhibitors of HDAC11

Matthew W. Martin, Jennifer Y. Lee, David R. Lancia et al. · Bioorganic & Medicinal Chemistry Letters · 2018 · 64 citations · Full text

Medicinal Chemistry, Biochemistry, Novel N-hydroxy-2-arylisoindoline-4-carboxamides +9

Ring expansion of aziridines to piperidines using the aza-wittig rearrangement

Iain Coldham, Alan Collis, R. J. MOULD et al. · Tetrahedron Letters · 1995 · 51 citations

Heterocyclic, Natural Sciences, Diversity-oriented Synthesis +5

Discovery of a Potent and Selective Tyrosine Kinase 2 Inhibitor: TAK-279

Silvana Leit, Jeremy R. Greenwood, Samantha Carriero et al. · Journal of Medicinal Chemistry · 2023 · 48 citations · Full text