Keith A. Canada

Design of an in vitro biocatalytic cascade for the manufacture of islatravir

Mark A. Huffman, Anna Fryszkowska, Oscar Alvizo et al. · Science · 2019 · 631 citations

Engineering, Biotechnology, Pharmaceutical Biotechnology +17

A specific antidote for dabigatran: functional and structural characterization

Felix Schiele, Joanne van Ryn, Keith A. Canada et al. · Blood · 2013 · 561 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +9

Directed Evolution of Toluene <i>ortho</i> -Monooxygenase for Enhanced 1-Naphthol Synthesis and Chlorinated Ethene Degradation

Keith A. Canada, Sachiyo Iwashita, Hojae Shim et al. · Journal of Bacteriology · 2002 · 177 citations · Full text

Life Sciences, Biochemistry, Biotechnology +13

Aerobic degradation of tetrachloroethylene by toluene-o-xylene monooxygenase of Pseudomonas stutzeri OX1

Doohyun Ryoo, Hojae Shim, Keith A. Canada et al. · Nature Biotechnology · 2000 · 153 citations

Life Sciences, Biochemistry, Microbiology +15

A kinase-cGAS cascade to synthesize a therapeutic STING activator

John A. McIntosh, Zhijian Liu, Brian M. Andresen et al. · Nature · 2022 · 135 citations

Life Sciences, Molecular Biology, Pharmacology +10