Huizhen Zhao

SIRT1 Activators Suppress Inflammatory Responses through Promotion of p65 Deacetylation and Inhibition of NF-κB Activity

Hongying Yang, Wei Zhang, Heng Pan et al. · PLoS ONE · 2012 · 373 citations · Full text

Life Sciences, Cell Biology, Immunology +16

Crystallographic structure of a small molecule SIRT1 activator-enzyme complex

Han Dai, April Case, Thomas V. Riera et al. · Nature Communications · 2015 · 203 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +17

New IDH1 mutant inhibitors for treatment of acute myeloid leukemia

Ujunwa Cynthia Okoye-Okafor, Boris Bartholdy, Jessy Cartier et al. · Nature Chemical Biology · 2015 · 176 citations · Full text

Medicine, Hematology, Oncology +12

A Tale of Two Subunits: How the Neomorphic R132H IDH1 Mutation Enhances Production of αHG

Beth Pietrak, Huizhen Zhao, Hongwei Qi et al. · Biochemistry · 2011 · 109 citations

Life Sciences, Biochemistry, Genetics +15

ATP-competitive inhibitors of the mitotic kinesin KSP that function via an allosteric mechanism

Lusong Luo, Cynthia A. Parrish, Neysa Nevins et al. · Nature Chemical Biology · 2007 · 108 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16