Samuel Gusscott

High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling

Hind Medyouf, Samuel Gusscott, Hongfang Wang et al. · The Journal of Experimental Medicine · 2011 · 167 citations · Full text

Medicine, Cancer Biology, Oncology +17

Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss

Hind Medyouf, Xiuhua Gao, Florence Armstrong et al. · Blood · 2009 · 92 citations · Full text

Life Sciences, Molecular Biology, Oncology +14

IGF1R Derived PI3K/AKT Signaling Maintains Growth in a Subset of Human T-Cell Acute Lymphoblastic Leukemias

Samuel Gusscott, Catherine E. Jenkins, Sonya H.L. Lam et al. · PLoS ONE · 2016 · 50 citations · Full text

Medicine, Cancer Biology, Oncology +16

Notch-mediated repression of miR-223 contributes to IGF1R regulation in T-ALL

Samuel Gusscott, Florian Kuchenbauer, R. Keith Humphries et al. · Leukemia Research · 2012 · 40 citations

Life Sciences, Molecular Biology, Oncology +16

Inactivation of the Kinase Domain of CDK10 Prevents Tumor Growth in a Preclinical Model of Colorectal Cancer, and Is Accompanied by Downregulation of Bcl-2

Louis‐Bastien Weiswald, Mohammad R. Hasan, John C.T. Wong et al. · Molecular Cancer Therapeutics · 2017 · 23 citations · Full text

Medicine, Cancer Biology, Oncology +17