Patrick Berna

Crystal Structure of the Open Form of Dog Gastric Lipase in Complex with a Phosphonate Inhibitor

Alain Roussel, Nabil Miled, Liliane Berti-Dupuis et al. · Journal of Biological Chemistry · 2002 · 116 citations · Full text

Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 1: Design, synthesis and structure–activity relationship studies

Fabrice Vergne, Patrick Bernardelli, Edwige Lorthiois et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 57 citations · Full text

Novel Structural Class, Medicinal Chemistry, Medicine +9

Large-scale production of a therapeutic protein in transgenic tobacco plants: effect of subcellular targeting on quality of a recombinant dog gastric lipase

Véronique Gruber, Patrick Berna, Thierry Arnaud et al. · Molecular Breeding · 2001 · 55 citations

Analysis of the inflammatory response induced by rhMMP-12 catalytic domain instilled in mouse airways

Soazig Nénan, Jean‐Michel Planquois, Patrick Berna et al. · International Immunopharmacology · 2004 · 52 citations

Asthma, Inflammation, Mouse Airways +10

Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 1

Edwige Lorthiois, Patrick Bernardelli, Fabrice Vergne et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 50 citations · Full text

Medicinal Chemistry, Medicine, Rational Drug Design +7