Masha V. Poyurovsky

DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer

Chao Mao, Xiaoguang Liu, Yilei Zhang et al. · Nature · 2021 · 1.6K citations · Full text

Reductive Stress, Biochemistry, Dhodh-mediated Ferroptosis Defence +6

Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis

Xiaoguang Liu, Litong Nie, Yilei Zhang et al. · Nature Cell Biology · 2023 · 1K citations · Full text

Actin Cytoskeleton Vulnerability, Protein Secretion, Natural Sciences +9

Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species

Sawako Suzuki, Tomoaki Tanaka, Masha V. Poyurovsky et al. · Proceedings of the National Academy of Sciences · 2010 · 669 citations · Full text

Lipid Peroxidation, Cell Death, Molecular Biology +17

Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer

Xiaoguang Liu, Kellen Olszewski, Yilei Zhang et al. · Nature Cell Biology · 2020 · 558 citations · Full text

Disulfide Stress, Targetable Metabolic Vulnerability, Cystine Transporter Regulation +12

A targetable CoQ-FSP1 axis drives ferroptosis- and radiation-resistance in KEAP1 inactive lung cancers

Pranavi Koppula, Guang Lei, Yilei Zhang et al. · Nature Communications · 2022 · 423 citations · Full text