Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

Evanna L. Mills, Beth Kelly, Angela Logan, +17

Cell

InflammationMitochondrial FunctionBiochemistryMitochondrial DynamicLipid Peroxidation +7

Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex

Si Ming Man, Lee Hopkins, Eileen Nugent, +7

Proceedings of the National Academy of Sciences

Microbial PathogensInflammasome ActivationInnate Immune SystemImmunologyInnate Immunity +29

<i>Salmonella</i> Infection Induces Recruitment of Caspase-8 to the Inflammasome To Modulate IL-1β Production

Si Ming Man, Panagiotis Tourlomousis, Lee Hopkins, +3

The Journal of Immunology

Mitochondrial damage contributes to<i>Pseudomonas aeruginosa</i>activation of the inflammasome and is downregulated by autophagy

Majid S. Jabir, Lee Hopkins, Neil Ritchie, +9

Autophagy

MitophagyMitochondrial Damage ContributesImmunologyPathologyCell Death +15

Analysis of bacterial communities of traditional fermented West African cereal foods using culture independent methods

Folarin A. Oguntoyinbo, Panagiotis Tourlomousis, Michael J. Gasson, +1

International Journal of Food Microbiology

Food FermentationBacterial CommunitiesAgricultural EconomicsFood MicrobiologyMicrobial Ecology +7

Actin polymerization as a key innate immune effector mechanism to control <i>Salmonella</i> infection

Si Ming Man, Andrew Ekpenyong, Panagiotis Tourlomousis, +9

Proceedings of the National Academy of Sciences

Microbial PathogensInnate Immune SystemImmunologyImmune RegulationInnate Immunity +20

Caspase-1 Cleavage of the TLR Adaptor TRIF Inhibits Autophagy and β-Interferon Production during Pseudomonas aeruginosa Infection

Majid S. Jabir, Neil Ritchie, Dong Li, +8

Cell Host & Microbe

InflammationMedical MicrobiologyCaspase-1 CleavageVirulence FactorPathogenesis +10

Detection of a microbial metabolite by STING regulates inflammasome activation in response to Chlamydia trachomatis infection

Steve J. Webster, Sven Brode, Lou Ellis, +9

PLoS Pathogens

Microbial PathogensInflammasome ActivationInnate Immune SystemImmunologyImmune Regulation +23

Prevention of the foreign body response to implantable medical devices by inflammasome inhibition

Damiano G. Barone, Alejandro Carnicer‐Lombarte, Panagiotis Tourlomousis, +10

Proceedings of the National Academy of Sciences

Saturation of acyl chains converts cardiolipin from an antagonist to an activator of Toll-like receptor-4

Malvina Pizzuto, Caroline Lonez, Alberto Baroja‐Mazo, +7

Cellular and Molecular Life Sciences