A.J. Harker

Selective Plasma Hydrolysis of Glucocorticoid γ-Lactones and Cyclic Carbonates by the Enzyme Paraoxonase: An Ideal Plasma Inactivation Mechanism

Keith Biggadike, Richard Angell, Colin M. Burgess et al. · Journal of Medicinal Chemistry · 1999 · 180 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +13

Modification of the ultrafiltration technique to overcome solubility and non-specific binding challenges associated with the measurement of plasma protein binding of corticosteroids

S. Taylor, A.J. Harker · Journal of Pharmaceutical and Biomedical Analysis · 2005 · 85 citations

Ultrafiltration Technique, Biochemistry, Medicine +9

High-performance liquid chromatographic assay for 2′-deoxy-3′-thiacytidine in human serum

A.J. Harker, G.L. Evans, A.E. Hawley et al. · Journal of Chromatography B Biomedical Sciences and Applications · 1994 · 63 citations

Biochemistry, Medicine, Bioanalysis +9

Pharmacokinetics of lamivudine and BCH-189 in plasma and cerebrospinal fluid of nonhuman primates

Susan M. Blaney, M J Daniel, A.J. Harker et al. · Antimicrobial Agents and Chemotherapy · 1995 · 50 citations · Full text

Immunology, Pharmacotherapy, Antiviral Drug +18

Discovery of<i>N</i>-[(2<i>S</i>)-5-(6-Fluoro-3-pyridinyl)-2,3-dihydro-1<i>H</i>-inden-2-yl]-2-propanesulfonamide, a Novel Clinical AMPA Receptor Positive Modulator

Simon E. Ward, Mark H Harries, Laura Aldegheri et al. · Journal of Medicinal Chemistry · 2010 · 47 citations · Full text