Simon E. Ward

Synthesis of Polyprenylated Acylphloroglucinols Using Bridgehead Lithiation:  The Total Synthesis of Racemic Clusianone and a Formal Synthesis of Racemic Garsubellin A

Nadia M. Ahmad, Vincent Rodeschini, Nigel S. Simpkins et al. · The Journal of Organic Chemistry · 2007 · 96 citations

Natural Sciences, Chemistry, Medicinal Chemistry +16

Clinical and Cellular Roles for TDP1 and TOP1 in Modulating Colorectal Cancer Response to Irinotecan

Cornelia Meisenberg, Duncan C. Gilbert, Anthony J. Chalmers et al. · Molecular Cancer Therapeutics · 2014 · 76 citations · Full text

Medicine, Molecular Biology, Oncology +17

Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion

G. Stuart Cockerill, Richard Angell, Alexandre F. Bedernjak et al. · Journal of Medicinal Chemistry · 2021 · 75 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of AMPA Receptor Positive Allosteric Modulators

Simon E. Ward, Mark H Harries, Laura Aldegheri et al. · Journal of Medicinal Chemistry · 2010 · 66 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Selective Cleavage of Benzyl Ethers

Miles Congreve, Edwin C. Davison, Mary Ann M. Fuhry et al. · Synlett · 1993 · 62 citations

Natural Sciences, Chemistry, Organic Chemistry +9