Jag Heer

Identification of Novel Inhibitors of the Transforming Growth Factor β1 (TGF-β1) Type 1 Receptor (ALK5)

James F. Callahan, Joelle L. Burgess, James A. Fornwald et al. · Journal of Medicinal Chemistry · 2002 · 309 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids

Jitske Jansen, Katharina C. Reimer, James S. Nagai et al. · Cell stem cell · 2021 · 266 citations · Full text

Medicine, Infectious Diseases, Pathology +17

Importance of Rigidity in Designing Small Molecule Drugs To Tackle Protein–Protein Interactions (PPIs) through Stabilization of Desired Conformers

Alastair D. G. Lawson, Malcolm MacCoss, Jag Heer · Journal of Medicinal Chemistry · 2017 · 148 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Discovery of an MLLT1/3 YEATS Domain Chemical Probe

Moses Moustakim, Thomas Christott, Octovia Monteiro et al. · Angewandte Chemie International Edition · 2018 · 95 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +17

Discovery of a PCAF Bromodomain Chemical Probe

Moses Moustakim, Peter G. K. Clark, Laura Trulli et al. · Angewandte Chemie International Edition · 2016 · 91 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13