John C. Pettersen

Discovery of a Clinical Candidate from the Structurally Unique Dioxa-bicyclo[3.2.1]octane Class of Sodium-Dependent Glucose Cotransporter 2 Inhibitors

Vincent Mascitti, Tristan S. Maurer, Ralph P. Robinson et al. · Journal of Medicinal Chemistry · 2011 · 134 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of (<i>S</i>)-6-(3-Cyclopentyl-2-(4-(trifluoromethyl)-1<i>H</i>-imidazol-1-yl)propanamido)nicotinic Acid as a Hepatoselective Glucokinase Activator Clinical Candidate for Treating Type 2 Diabetes Mellitus

Jeffrey A. Pfefferkorn, Angel Guzmán-Pérez, John Litchfield et al. · Journal of Medicinal Chemistry · 2011 · 115 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14

Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2)

Kentaro Futatsugi, Daniel W. Kung, Suvi T. M. Orr et al. · Journal of Medicinal Chemistry · 2015 · 83 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Designing glucokinase activators with reduced hypoglycemia risk: discovery of N,N-dimethyl-5-(2-methyl-6-((5-methylpyrazin-2-yl)-carbamoyl)benzofuran-4-yloxy)pyrimidine-2-carboxamide as a clinical candidate for the treatment of type 2 diabetes mellitus

Jeffrey A. Pfefferkorn, Angel Guzmán-Pérez, Peter J. Oates et al. · MedChemComm · 2011 · 68 citations

Pharmacy, Biochemistry, Medicinal Chemistry +12

The effects of cyanide on brain mitochondrial cytochrome oxidase and respiratory activities

John C. Pettersen, Steven D. Cohen · Journal of Applied Toxicology · 1993 · 55 citations

Pharmacy, Pharmacology, Toxicology +17