Marc Garard

Cardiac Myosin Activation: A Potential Therapeutic Approach for Systolic Heart Failure

Fady I. Malik, James J. Hartman, Kathleen A. Elias et al. · Science · 2011 · 596 citations

Medicine, Cardiology, Pharmacology +17

Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases

Alan J. Russell, James J. Hartman, Aaron C. Hinken et al. · Nature Medicine · 2012 · 137 citations

Medicine, Neurology, Neuroscience +12

Discovery of<i>Omecamtiv Mecarbil</i>the First, Selective, Small Molecule Activator of Cardiac Myosin

B. Paul Morgan, Alexander R. Muci, Pu‐Ping Lu et al. · ACS Medicinal Chemistry Letters · 2010 · 112 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of<i>Tirasemtiv</i>, the First Direct Fast Skeletal Muscle Troponin Activator

Scott E. Collibee, Gustave Bergnes, Alexander R. Muci et al. · ACS Medicinal Chemistry Letters · 2018 · 30 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +8

Discovery of Reldesemtiv, a Fast Skeletal Muscle Troponin Activator for the Treatment of Impaired Muscle Function

Scott E. Collibee, Gustave Bergnes, Chih-Yuan Chuang et al. · Journal of Medicinal Chemistry · 2021 · 25 citations · Full text

Pharmacy, Medicinal Chemistry, Neurology +13