Christopher Massad

The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans

Laurence Ménard, David Saadoun, Isabelle Isnardi et al. · Journal of Clinical Investigation · 2011 · 278 citations · Full text

Lymphocyte Development, Immunology, B Cell Activation +18

Self-reactive VH4-34–expressing IgG B cells recognize commensal bacteria

Jean‐Nicolas Schickel, Salomé Glauzy, Yen-Shing Ng et al. · The Journal of Experimental Medicine · 2017 · 87 citations · Full text

Rituximab does not reset defective early B cell tolerance checkpoints

Nicolas Chamberlain, Christopher Massad, Tyler Oe et al. · Journal of Clinical Investigation · 2015 · 86 citations · Full text

Adaptive Immune System, Humoral Response, Immunology +23

Activation-Induced Cytidine Deaminase Expression in Human B Cell Precursors Is Essential for Central B Cell Tolerance

Tineke Cantaert, Jean-Nicolas Schickel, Jason M. Bannock et al. · Immunity · 2015 · 78 citations · Full text

Cell Regulation, Immunology, Self-tolerance +4

PTPN22 inhibition resets defective human central B cell tolerance

Jean‐Nicolas Schickel, Marcel Kuhny, Alessia Baldo et al. · Science Immunology · 2016 · 58 citations · Full text