Concepedia

Jason R. Thomas

JR

30

Publications

3.1K

Citations

24

H-Index

2004

Active since

Affiliations

Novartis (Switzerland)(Current)

Novartis (United States)

Novartis Institutes for BioMedical Research

University of Illinois Urbana-Champaign

Novartis (China)

Jason R. Thomas is an author at Novartis (Switzerland) specializing in medicine, molecular biology, and natural sciences.

Top concepts

MedicineMolecular BiologyBiochemistryNatural SciencesDrug DiscoveryCell BiologySystems BiologyProteomicsTumor BiologyBiomolecular Engineering

Publications per year

2004–2024

30

Publications

30

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

William E. Dowdle, Beat Nyfeler, Jane Nagel et al. · Nature Cell Biology · 2014 · 715 citations

Inflammation, Cell Autophagy, Signal Transduction +13

SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice

James Palacino, Susanne E. Swalley, Cheng Song et al. · Nature Chemical Biology · 2015 · 422 citations

Transcriptional Regulation, Genetics, Gene Regulation +7

Harnessing the anti-cancer natural product nimbolide for targeted protein degradation

Jessica N. Spradlin, Xirui Hu, Carl C. Ward et al. · Nature Chemical Biology · 2019 · 404 citations

Drug Targeting, Health Sciences, Biochemistry +9

Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications

Carl C. Ward, Jordan I. Kleinman, Scott M. Brittain et al. · ACS Chemical Biology · 2019 · 319 citations · Full text

Protein Function, Biochemistry, Biomolecular Tool +13

Size-Specific Ligands for RNA Hairpin Loops

Jason R. Thomas, Xianjun Liu, Paul J. Hergenrother · Journal of the American Chemical Society · 2005 · 150 citations

Chemical Biology, Medicinal Chemistry, Biochemistry +12

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