Scott M. Brittain

Harnessing the anti-cancer natural product nimbolide for targeted protein degradation

Jessica N. Spradlin, Xirui Hu, Carl C. Ward et al. · Nature Chemical Biology · 2019 · 424 citations

Pharmacy, Molecular Biology, Oncology +17

Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications

Carl C. Ward, Jordan I. Kleinman, Scott M. Brittain et al. · ACS Chemical Biology · 2019 · 336 citations · Full text

Life Sciences, Chemical Biology, Molecular Biology +16

Deubiquitinase-targeting chimeras for targeted protein stabilization

Nathaniel J. Henning, Lydia Boike, Jessica N. Spradlin et al. · Nature Chemical Biology · 2022 · 321 citations · Full text

Life Sciences, Chemical Biology, Molecular Biology +10

Control of protein phosphorylation with a genetically encoded photocaged amino acid

Edward A. Lemke, Daniel Summerer, Bernhard H. Geierstanger et al. · Nature Chemical Biology · 2007 · 254 citations

Life Sciences, Biochemistry, Molecular Biology +9

FIRST REPORT OF THE CYANOTOXINS CYLINDROSPERMOPSIN AND DEOXYCYLINDROSPERMOPSIN FROM <i>RAPHIDIOPSIS CURVATA</i> (CYANOBACTERIA)

Renhui Li, Wayne W. Carmichael, Scott M. Brittain et al. · Journal of Phycology · 2001 · 236 citations

Life Sciences, Microbiology, Toxicology +16