Attenuation of CD4+CD25+ Regulatory T Cells in the Tumor Microenvironment by Metformin, a Type 2 Diabetes Drug

Yuki Kunisada, Shingo Eikawa, Nahoko Tomonobu, +7

EBioMedicine

Metformin induces CD11b+-cell-mediated growth inhibition of an osteosarcoma: implications for metabolic reprogramming of myeloid cells and anti-tumor effects

Takenori Uehara, Shingo Eikawa, Mikako Nishida, +6

International Immunology

Low‐intensity pulsed ultrasound stimulation promotes osteoblast differentiation through hedgehog signaling

Kenichi Matsumoto, Tsuyoshi Shimo, Naito Kurio, +10

Journal of Cellular Biochemistry

Medical UltrasoundEngineeringBone RepairBiomedical EngineeringOrthopaedic Surgery +16

Ammonium tetrathiomolybdate enhances the antitumor effect of cisplatin via the suppression of ATPase copper transporting beta in head and neck squamous cell carcinoma

Shoji Ryumon, Tatsuo Okui, Yuki Kunisada, +8

Oncology Reports

Ammonium TetrathiomolybdateTumor BiologyDrug ResistanceOncologyMetronomic Therapy +14

The HMGB1/RAGE axis induces bone pain associated with colonization of 4T1 mouse breast cancer in bone

Tatsuo Okui, Masahiro Hiasa, Shoji Ryumon, +7

Journal of bone oncology

Tachykinin Receptor 3 Distribution in Human Oral Squamous Cell Carcinoma

Kyoichi Obata, Tsuyoshi Shimo, Tatsuo Okui, +7

Anticancer Research

Oral Squamous Cell Carcinoma-derived Sonic Hedgehog Promotes Angiogenesis

Hiromasa Kuroda, Naito Kurio, Tsuyoshi Shimo, +11

Anticancer Research

High-mobility group box 1 induces bone destruction associated with advanced oral squamous cancer via RAGE and TLR4

Yumi Sakamoto, Tatsuo Okui, Toshiyuki Yoneda, +10

Biochemical and Biophysical Research Communications

Advanced OsccImmunologyCell DeathCancer BiologyTumor Biology +17

Reproduction of the Antitumor Effect of Cisplatin and Cetuximab Using a Three-dimensional Spheroid Model in Oral Cancer

Kisho Ono, Kohei Sato, Tomoya Nakamura, +14

International Journal of Medical Sciences

Expression and Role of IL-1β Signaling in Chondrocytes Associated with Retinoid Signaling during Fracture Healing

Tsuyoshi Shimo, Hiroaki Takebe, Tatsuo Okui, +10

International Journal of Molecular Sciences

InflammationRegenerative MedicineRheumatologyInflammatory DiseaseBone Tissue Reconstruction +12