Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3

Masahiro Hiasa, Tatsuo Okui, Yohance M. Allette, +6

Cancer Research

The lactate sensor GPR81 regulates glycolysis and tumor growth of breast cancer

Shota Ishihara, Kenji Hata, Katsutoshi Hirose, +5

Scientific Reports

Inhibition of the Growth Factor MDK/Midkine by a Novel Small Molecule Compound to Treat Non-Small Cell Lung Cancer

Huifang Hao, Yutaka Maeda, Takuya Fukazawa, +15

PLoS ONE

ImmunologyCell DeathHeparin-binding Growth FactorCancer BiologyTumor Biology +16

Chelating luminal zinc mimics hydrogen sulfide-evoked colonic pain in mice: possible involvement of T-type calcium channels

Masatoshi Matsunami, Saori Kirishi, Tatsuo Okui, +1

Neuroscience

Sulfide-evoked Colonic PainHealth SciencesPain MedicineMedicinePhysiology +9

Hypoxia-induced up-regulation of angiogenin, besides VEGF, is related to progression of oral cancer

Koji Kishimoto, Shoko Yoshida, Soichiro Ibaragi, +4

Oral Oncology

AngiogenesisMedicineHypoxia (Medicine)Hypoxia-induced Up-regulationPathology +7

PTHrP regulates angiogenesis and bone resorption via VEGF expression.

Sachiko Isowa, Tsuyoshi Shimo, Soichiro Ibaragi, +6

PubMed

SOX2 suppresses CDKN1A to sustain growth of lung squamous cell carcinoma

Takuya Fukazawa, Minzhe Guo, Naomasa Ishida, +10

Scientific Reports

Anti-tumor effect in human breast cancer by TAE226, a dual inhibitor for FAK and IGF-IR in vitro and in vivo

Naito Kurio, Tsuyoshi Shimo, Takuya Fukazawa, +8

Experimental Cell Research

Dual InhibitorAnti-tumor EffectBreast OncologyMedicineHuman Breast Cancer +7

Abnormalities of the FHIT gene in human oral carcinogenesis

Keiji Tanimoto, Shinichi Hayashi, Eiju Tsuchiya, +6

British Journal of Cancer

Sonic Hedgehog Regulates Osteoblast Function by Focal Adhesion Kinase Signaling in the Process of Fracture Healing

Yuu Horikiri, Tsuyoshi Shimo, Naito Kurio, +4

PLoS ONE