Mikako Nishida

Immune-mediated antitumor effect by type 2 diabetes drug, metformin

Shingo Eikawa, Mikako Nishida, Shusaku Mizukami et al. · Proceedings of the National Academy of Sciences · 2015 · 522 citations · Full text

Immunology, Immune Regulation, Immunoediting +27

Metformin induces CD11b+-cell-mediated growth inhibition of an osteosarcoma: implications for metabolic reprogramming of myeloid cells and anti-tumor effects

Takenori Uehara, Shingo Eikawa, Mikako Nishida et al. · International Immunology · 2018 · 115 citations · Full text

Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes

Mikako Nishida, Nahoko Yamashita, Taisaku Ogawa et al. · Journal for ImmunoTherapy of Cancer · 2021 · 96 citations · Full text

Metformin-ROS-Nrf2 connection in the host defense mechanism against oxidative stress, apoptosis, cancers, and ageing

Heiichiro Udono, Mikako Nishida · Biochimica et Biophysica Acta (BBA) - General Subjects · 2022 · 26 citations

Metformin-ros-nrf2 Connection, Medicine, Apoptosis +8

Nutrient Condition in the Microenvironment Determines Essential Metabolisms of CD8+ T Cells for Enhanced IFNγ Production by Metformin

Ruoyu Chao, Mikako Nishida, Nahoko Yamashita et al. · Frontiers in Immunology · 2022 · 18 citations · Full text