Michael C. Kann

CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours

Rebecca C. Larson, Michael C. Kann, Stefanie R. Bailey et al. · Nature · 2022 · 349 citations

Life Sciences, Immunology, Oncology +16

Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide

Max Jan, Irene Scarfò, Rebecca C. Larson et al. · Science Translational Medicine · 2021 · 258 citations · Full text

Medicine, Oncology, Pharmacology +17

Distinct cellular dynamics associated with response to CAR-T therapy for refractory B cell lymphoma

Nicholas J. Haradhvala, Mark B. Leick, Katie Maurer et al. · Nature Medicine · 2022 · 255 citations · Full text

Life Sciences, Immunology, Oncology +16

Non-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemia

Mark B. Leick, Harrison Silva, Irene Scarfò et al. · Cancer Cell · 2022 · 135 citations · Full text

Medicine, Hematology, Oncology +14

Mesothelin CAR T Cells Secreting Anti-FAP/Anti-CD3 Molecules Efficiently Target Pancreatic Adenocarcinoma and its Stroma

Marc Wehrli, Samantha Guinn, Filippo Birocchi et al. · Clinical Cancer Research · 2024 · 103 citations · Full text

Medicine, Immunology, Oncology +17