Concepedia

Irene Scarfò

IS

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Publications

22

Citations

3.2K

H-Index

18

Active since

2015

Affiliations

Harvard University(Current)

Massachusetts General Hospital

Broad Institute

Dana-Farber Cancer Institute

Massachusetts Institute of Technology

Irene Scarfò is an author at Harvard University specializing in medicine, cell biology, and immunology.

ORCID

Top concepts

Publications per year

2015–2025

22

Publications

22

Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing

Benjamin P. Kleinstiver, Alexander A. Sousa, Russell T. Walton et al. · Nature Biotechnology · 2019 · 690 citations

, , +12

CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity

Bryan D. Choi, Xiaoling Yu, Ana P. Castaño et al. · Nature Biotechnology · 2019 · 539 citations

, , +9

CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours

Rebecca C. Larson, Michael C. Kann, Stefanie R. Bailey et al. · Nature · 2022 · 330 citations

, , +11

CRISPR-Cas9 disruption of PD-1 enhances activity of universal EGFRvIII CAR T cells in a preclinical model of human glioblastoma

Bryan D. Choi, Xiaoling Yu, Ana P. Castaño et al. · Journal for ImmunoTherapy of Cancer · 2019 · 271 citations · Full text

Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide

Max Jan, Irene Scarfò, Rebecca C. Larson et al. · Science Translational Medicine · 2021 · 243 citations · Full text

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