Interactions between Siglec-7/9 receptors and ligands influence NK cell–dependent tumor immunosurveillance

Camilla Jandus, Kayluz Frias Boligan, Obinna Chijioke, +11

Journal of Clinical Investigation

Non-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemia

Mark B. Leick, Harrison Silva, Irene Scarfò, +13

Cancer Cell

Hematological MalignancyCell TherapyAcute Myeloid LeukemiaImmunologyAdult T-cell Leukemia-lymphoma +4

Single-center experience using anakinra for steroid-refractory immune effector cell-associated neurotoxicity syndrome (ICANS)

Marc Wehrli, Kathleen Gallagher, Yi‐Bin Chen, +13

Journal for ImmunoTherapy of Cancer

ImmunotoxicologyImmunologyImmune RegulationSteroid-refractory IcansPharmacotherapy +16

Macrophages and dendritic cells express tight junction proteins and exchange particles in an in vitro model of the human airway wall

Fabian Blank, Marc Wehrli, Andrea Lehmann, +4

Immunobiology

AsthmaInflammationInflammatory Lung DiseaseLung InflammationCell Signaling +9

Mesothelin CAR T Cells Secreting Anti-FAP/Anti-CD3 Molecules Efficiently Target Pancreatic Adenocarcinoma and its Stroma

Marc Wehrli, Samantha Guinn, Filippo Birocchi, +36

Clinical Cancer Research

Drosophila PS1 integrin is a laminin receptor and differs in ligand specificity from PS2.

Philip J. Gotwals, Liselotte I. Fessler, Marc Wehrli, +1

Proceedings of the National Academy of Sciences

Cell AdhesionCytoskeletonDrosophila Ps1 IntegrinCellular PhysiologySchneider S2 Cells +19

Human IgA Fc Receptor FcαRI (CD89) Triggers Different Forms of Neutrophil Death Depending on the Inflammatory Microenvironment

Marc Wehrli, Fabiola Cortinas-Elizondo, Ruslan Hlushchuk, +7

The Journal of Immunology

Inflammatory MicroenvironmentInnate Immune SystemImmunologyImmune RegulationCell Death +25

Haplotype structure defines effects of common <i>DPYD</i> variants c.85T &gt; C (rs1801265) and c.496A &gt; G (rs2297595) on dihydropyrimidine dehydrogenase activity: Implication for 5‐fluorouracil toxicity

Seid Hamzic, Dominic Schärer, Steven M. Offer, +8

British Journal of Clinical Pharmacology

Comparative analysis of Bcl-2 family protein overexpression in CAR T cells alone and in combination with BH3 mimetics

Felix Korell, Michael Olson, Diego Salas‐Benito, +14

Science Translational Medicine

T-regulatory CellImmunologyImmunoeditingCell DeathAntigen Processing +14

CD70 CAR T cells secreting an anti-CD33/anti-CD3 dual-targeting antibody overcome antigen heterogeneity in AML

Harrison Silva, Grace Martin, Filippo Birocchi, +16

Blood