Trina A. Knotts

Inhibition of Ceramide Synthesis Ameliorates Glucocorticoid-, Saturated-Fat-, and Obesity-Induced Insulin Resistance

William L. Holland, Joseph T. Brozinick, Liping Wang et al. · Cell Metabolism · 2007 · 1.2K citations · Full text

Obesity, Metabolic Syndrome, Biochemistry +11

Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid–induced ceramide biosynthesis in mice

William L. Holland, Benjamin T. Bikman, Liping Wang et al. · Journal of Clinical Investigation · 2011 · 676 citations · Full text

Immunology, Tlr4 Recognition, Innate Immunity +20

A Role for Ceramide, but Not Diacylglycerol, in the Antagonism of Insulin Signal Transduction by Saturated Fatty Acids

Jose A. Chavez, Trina A. Knotts, Liping Wang et al. · Journal of Biological Chemistry · 2003 · 601 citations · Full text

A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice

Megan N. Roberts, Marita A. Wallace, Alexey Tomilov et al. · Cell Metabolism · 2017 · 506 citations · Full text

Lifespan Extension, Nutrition, Aging +8

Acylcarnitines activate proinflammatory signaling pathways

Jennifer M. Rutkowsky, Trina A. Knotts, Kikumi D. Ono‐Moore et al. · American Journal of Physiology-Endocrinology and Metabolism · 2014 · 314 citations